Brinzolamide
Systematic (IUPAC) name
(5R)-5-ethylamino-3-(3-methoxypropyl)- 2,2-dioxo-2λ6,9-dithia- 3-azabicyclo[4.3.0]nona-7,10-diene- 8-sulfonamide
Identifiers
CAS number	138890-62-7
ATC code	S01EC04
PubChem	68844
DrugBank	APRD00475
Chemical data
Formula	C12H21N3O5S3
Mol. mass	383.51 g/mol
Pharmacokinetic data
Bioavailability	?
Protein binding	~60%
Metabolism	?
Half life	111 days
Excretion	?
Therapeutic considerations
Licence data	EU, US
Pregnancy cat.	C(US)
Legal status	℞-only(US)
Routes	Ophthalmic

Brinzolamide is a carbonic anhydrase inhibitor.

References

• Ermis S, Ozturk F, Inan U (2005). "Comparing the effects of travoprost and brinzolamide on intraocular pressure after phacoemulsification.". Eye 19 (3): 303–7. doi:10.1038/sj.eye.6701470. PMID 15258611. 
• Iester M, Altieri M, Michelson G, Vittone P, Traverso C, Calabria G. "Retinal peripapillary blood flow before and after topical brinzolamide.". Ophthalmologica 218 (6): 390–6. doi:10.1159/000080942. PMID 15564757. 
• Kaup M, Plange N, Niegel M, Remky A, Arend O (2004). "Effects of brinzolamide on ocular haemodynamics in healthy volunteers.". Br J Ophthalmol 88 (2): 257–62. doi:10.1136/bjo.2003.021485. PMID 14736787. 

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