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CDB-4124 

CDB-4124
Systematic (IUPAC) name
17α-acetoxy-21-methoxy-11β-[4-N,N-dimethylaminophenyl]-19-norpregna-4,9-diene-3,20-dione)
Identifiers
CAS number 136960-00-4
ATC code  ?
PubChem 9577221
Chemical data
Formula C31H39NO5 
Mol. mass 505.65 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status

Investigational

Routes  ?

CDB-4124 (proposed trade names Proellex, Progenta) is an investigational selective progesterone receptor modulator, tested for treatment of progesterone sensitive myomata.[1]

As of September 2008, it is undergoing Phase II and III clinical trials.[2]

References

  1. ^ Attardi BJ, Burgenson J, Hild SA, Reel JR (2004). "In vitro antiprogestational/antiglucocorticoid activity and progestin and glucocorticoid receptor binding of the putative metabolites and synthetic derivatives of CDB-2914, CDB-4124, and mifepristone". J Steroid Biochem Mol Biol 88 (3): 277–88. doi:10.1016/j.jsbmb.2003.12.004. PMID 15120421. 
  2. ^ ClinicalTrials.gov



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