CNS is a three-letter abbreviation with multiple meanings, as described below:

In science:

• Cell, Nature, and Science, acronym used to describe the three most prestigious scientific journals involved in biomedical research
• Central nervous system, brain and spinal cord
• Clinical nurse specialist
• Coagulase-negative staphylococcus, term to describe all staphylococcus species that are not staphylococcus aureus
• Crystallography and NMR system, software library for computational structural biology
• Crigler-Najjar syndrome, rare hereditary disease
• Conserved noncoding sequence

In media:

• Cartoon Network Studios
• Catholic News Service
• China News Service
• Cybercast News Service

Elsewhere:

• Cairns International Airport, IATA code
• Canadian Nuclear Society, technical society of the Canadian Nuclear Association
• Chateau Neuf Spelemannslag, Norwegian folk music group
• Chinese National Standards
• Cicero-North Syracuse High School in Cicero, New York
• "Communication, navigation, surveillance", often associated with air traffic management as CNS/ATM
• Council for National Security, military regime that governed Thailand following the 2006 coup d'état
• Corporation for National Service, former name of the Corporation for National and Community Service, an independent agency of the United States government
• Covenant not to sue, Microsoft Open Specification Promise
• City of Norwich School, a secondary school in Norwich, England
• Szekler National Council, ( Hungarian: Székely Nemzeti Tanács, SZNT; Romanian: Consiliul Naţional Secuiesc, CNS) is the organization representing the ethnic Szeklers of Romania

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