The Manuherikia River is located in Otago in the South Island of New Zealand. It rises in the far north of the Maniototo, flowing southwest for 85 kilometres before its confluence with the Clutha River at Alexandra. During the 1860s the Manuherikia was one of the centres of the Central Otago Gold Rush.

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Coordinates: 45°16′S 169°24′E / -45.267, 169.4