Muscle may refer to:

• Muscle, a unit of the muscular system of the body.

In music:

• Muscles (musician)
• Muscles (song), a song by Diana Ross
• Muscle Museum, a song by English band Muse

In other fields:

• Muscle (documentary), a British television documentary about doorstaff working in the centre of the city of Bristol, England
• MUSCLE, a multiple sequence alignment tool.
• Muscle: Confessions of an unlikely bodybuilder, a book by Samuel W.Fussell

See also:

• M.U.S.C.L.E., small pink action figures produced in the United States in the 1980s

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