Phenindione

Phenindione

Phenindione

Systematic (IUPAC) name

2-phenylindene-1,3-dione

Identifiers

CAS number 83-12-5

ATC code B01AA02

PubChem 4760

DrugBank APRD00166

Chemical data

Formula C₁₅H₁₀O₂

Mol. mass 222.239 g/mol

Pharmacokinetic data

Bioavailability ?

Protein binding 88%

Metabolism ?

Half life 5 to 10 hours

Excretion ?

Therapeutic considerations

Pregnancy cat.
D(AU) Passes into breast milk

Legal status

Routes Oral

Phenindione is an anticoagulant which functions as a Vitamin K antagonist.

External links

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Other	Ditazole • Cloricromen • Dipyridamole • Indobufen • Picotamide • Triflusal

Vitamin K antagonists (inhibit II, VII, IX, X)	Acenocoumarol • Clorindione • Coumatetralyl • Dicoumarol (Dicumarol) • Diphenadione • Ethyl biscoumacetate • Phenprocoumon • Phenindione • Tioclomarol • Warfarin

Heparin group/ glycosaminoglycans	low molecular weight heparin (Bemiparin, Certoparin, Dalteparin, Enoxaparin, Nadroparin, Parnaparin, Reviparin, Tinzaparin) heparinoid (Danaparoid, Sulodexide, Dermatan sulfate)

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Factor Xa inhibitors	Apixaban • Otamixaban • Rivaroxaban • oligosaccharides (Fondaparinux, Idraparinux)

Other	Defibrotide • Ramatroban • Antithrombin III • Protein C (Drotrecogin alfa)

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