Phospholipase

Phospholipase A1

phospholipase A1 member A

Identifiers

Symbol PLA1A

Entrez 51365

HUGO 17661

OMIM 607460

RefSeq NM_015900

UniProt Q53H76

Other data

EC number 3.1.1.32

Locus Chr. 3 q13.13-13.2

Phospholipase A1 is a phospholipase enzyme which removes the 1-acyl.^[1]

Phospholipase Cleavage Sites. Note that an enzyme that displays both PLA1 and PLA2 activities is called a Phospholipase B

Phospholipase A1 is a component of snake venom, but it also serves in normal metabolism to produce fatty acids from phospholipids.

References

v • d • e Hydrolase: esterases (EC 3.1)

3.1.1: Carboxylic ester hydrolases	Cholinesterase (Acetylcholinesterase, Butyrylcholinesterase) - Pectinesterase - 6-phosphogluconolactonase - PAF acetylhydrolase Lipase (Gastric/Lingual, Pancreatic, Lysosomal, Hormone-sensitive, Endothelial, Hepatic, Lipoprotein, Monoacylglycerol, Diacylglycerol) Phospholipase (A1, A2, B)

3.1.2: Thioesterase	Palmitoyl thioesterase - Ubiquitin carboxy-terminal hydrolase L1

3.1.3: Phosphatase	Alkaline phosphatase - Acid phosphatase (Prostatic)/Tartrate resistant acid phosphatase/Purple acid phosphatases - Nucleotidase - Glucose 6-phosphatase - Fructose 1,6-bisphosphatase - Calcineurin - Phosphoprotein phosphatase (PP2A) - OCRL - Pyruvate dehydrogenase phosphatase - Fructose 2,6-bisphosphatase - Protein tyrosine phosphatase - PTEN

3.1.4: Phosphodiesterase	Autotaxin - Phospholipase (C, D) - Sphingomyelin phosphodiesterase - PDE1 - PDE2 - PDE3 - PDE5

3.1.6: Sulfatase	Arylsulfatase B - Steroid sulfatase - Galactosamine-6 sulfatase - Arylsulfatase A - Iduronate-2-sulfatase - N-acetylglucosamine-6-sulfatase

other	Nuclease

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