Proerythroblast

A proerythroblast (or rubriblast, or pronormoblast) is the earliest of four stages in development of the normoblast.

In histology, it is very difficult to distinguish it from the other "blast" cells (lymphoblast, myeloblast, monoblast, and megakaryoblast.) The cytoplasm is blue in an H&E stain, indicating that it is basophilic.

"Pronormoblast" vs. "proerythroblast"

Some sources consider the terms "pronormoblast" and "proerythroblast" to be synonyms.^[1] However, other sources^[2] consider "proerythroblast" to be a parent term, divided into the following two categories:

• "pronormoblast" - normal develoment
• "promegaloblast" - abnormal development

Additional images

Blood cell lineage

References

1. ^ Pronormoblast at eMedicine Dictionary
2. ^ p_35/12668575 at Dorland's Medical Dictionary

External links

• Histology at BU 01804loa - "Bone Marrow and Hemopoiesis: bone marrow smear, erythroblast series with proerythroblast"
• Histology at OU 75_11
• Histology at KUMC blood-blood04
• Image and description at purdue.edu
• Histology of "promegaloblast" at marist.edu (pernicious anemia)
• Interactive image at usuarios.lycos.es
• Overview at temple.edu

This developmental biology article is a stub. You can help Wikipedia by expanding it.