Two-pore channels: This small family of 2 members putatively forms cation-selective ion channels. They are predicted to contain two KV-style six-transmembrane domains, suggesting they form a dimer in the membrane. These channels are related to catsper channels channels and, more distantly, TRP channels.
External links
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Membrane transport protein: ion channels |
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| Ca2+: Calcium channel |
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L-type/ Cavα ( 1.1, 1.2, 1.3, 1.4) • N-type/ Cavα2.2 • P-type/ Cavα( 2.1) • Q-type/ Cavα2.1 • R-type/ Cavα2.3 • T-type/ Cavα( 3.2)
α2δ-subunits ( 1, 2) • β-subunits ( β1, β2, β3, β4) • γ-subunits ( γ1, γ2, γ3, γ4)
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Other
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| Na+: Sodium channel |
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Navα ( 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 7A) • Navβ ( 1, 2, 3, 4)
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Other
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| K+: Potassium channel |
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Kvα (1-6) ( 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.10, 2.1, 2.2, 3.1, 3.2, 3.3, 3.4, 4.1, 4.2, 4.3, 5.1, 6.1, 6.2, 6.3, 6.4)
Kvα (7-12) ( 7.1, 7.2, 7.3, 7.4, 7.5, 8.1, 8.2, 9.1, 9.2, 9.3, 10.1, 10.2, 11.1/hERG, 11.2, 11.3, 12.1, 12.2, 12.3)
Kvβ ( 1, 2, 3) • KCNIP ( 1, 2, 3, 4) • minK/ISK • MiRP ( 1, 2, 3) • Shaker gene
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Kir ( 1.1, 2.1, 2.2, 2.3, 2.4) • GIRK/ Kir ( 3.1, 3.2, 3.3, 3.4) • Kir ( 4.1, 4.2, 5.1, 6.1, 6.2, 7.1)
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K2P ( 1, 2, 3, 4, 5, 6, 7, 9, 10, 12, 13, 15, 16, 17, 18)
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| M+: TRP cation channel |
TRPA ( 1) • TRPC ( 1, 2, 3, 4, 4AP, 5, 6, 7) • TRPM ( 1, 2, 3, 4, 5, 6, 7, 8) • TRPML ( 1, 2, 3) • TRPP ( 1, 2) • TRPV ( 1, 2, 3, 4, 5, 6)
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| Cl-: Chloride channel |
CFTR • CLCA ( 1, 2, 3, 4) • CLCN ( 1, 2, 3, 4, 5, 6, 7, KA, KB) • CLIC ( 1, 2, 3, 4, 5, 6) • CLNS ( 1A, 1B)
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| Cyclic nucleotide-gated |
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| Porin |
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| Other/general |
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